Folding of membrane
G. von Heijne
Dept. of Biochemistry, Stockholm University
Most integral membrane proteins consist of tightly packed bundles
transmembrane alpha-helices. Although only a handful of
structures are available, some architectural features that will
apply to membrane proteins in general are already apparent.
background, molecular genetic techniques can provide very
information on, e.g., the positioning of transmembrane helices in
bilayer and on the conformational properties of various kinds of
acids when part of a transmembrane helix.